Shoulder shots with my 06 always down deer instantaneously. I have never had one get away or even move around a lot after the impact. I have also arrowed one and I never will again. The pain they go through is ridiculous in archery, and I felt terrible about it (was my first deer).

FreeLancer: I'm not basing it off of BC2... I've fired lots of 12 gauge slugs and hit chest sized targets at 100 yards using a cylinder bore. IDK what crappy slugs you are using, but you should buy better ones. That "big chunk of lead" will kill an animal way faster and more ethically than a .22 LR any time.