If all you want to play is H2V on high, you don't need a crazy DX10 card. If you want DX10, go for a Geforce 8600 GT, but high-end DX9 cards like the Geforce 7900 and even midrange cards like the 7600 will run H2V quite well.
If you go for, say, an 8800, H2V does nothing to show what such a card is capable of. Something like FEAR or Oblivion is a better way to test the higher end cards.
Besides, the best of the best video cards (8800 GTX, HD 2900) need beefy power supplies and may not even fit inside your computer case (physically).
edit: The best game to test the best video cards is the upcoming Crysis.
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