It's not that females aren't up to it or that they couldn't be developed into "super-soldiers". It's that there's no way they should have beaten out any men as viable candidates for the program.
I mean, they're basically turning these women into giant men. Hormonally, low levels of estrogen and high levels of testosterone would almost certainly be the goal. Why not just start out with a male who's closer to what you're trying to accomplish? Why spend money and resources just to close a gap when you can start on the other side of the chasm?
That's all.
EDIT: Just to be clear, I was aware that female Spartans are "canon". I've thought it stupid for a while now.
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