Slayer is mindless because everyone is pointlessly killing each other for no other reason than acquiring...points. No higher objective, no story, no motive. Just killing for killing's sake. It's good sport.
He's talking about "mindless" in the sense that there's no effort, thought, or varying strategy involved, e.g. strafing over and behind the large hill in Blood Gulch and essentially dominating the entire map, or spamming grenades for in Rat Race.
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